Data Material
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Prevalence of Eosinophilic Esophagitis in Sublingual Immunotherapy Tablet Clinical Trials is Similar to the Background Prevalence in an Atopic Population
Congress Material• Eosinophilic esophagitis (EoE) is an allergen-mediated inflammatory condition of the esophagus
• The prevalence of EoE in the general population is approximately 0.1% and is observed to be
higher in adults than children
• Patients with EoE often have comorbid allergic disease (i.e., allergic rhinitis, asthma, eczema,
food allergy), known as atopy
• The presence of atopic disease is known to increase the risk of developing EoE
• There is currently limited prevalence data for EoE in atopic populations, although recent studies
have estimated the prevalence of EoE in atopic populations as 8.0-16.5% in adults and 0.2% to
5% in children
• Sublingual immunotherapy (SLIT)-tablets are an effective treatment for allergic rhinitis with or
without conjunctivitis (AR/C)
• Reports of EoE associated with SLIT-tablets are rare